My in-laws received this Westinghouse DPF-0802 Digital Picture Frame for Christmas. 
They also received a 1Gig card which came preloaded with 512mb of family photos.
The frame has a resolution of 800x600 pixels and has 128mb of internal flash memory. It supports the following memory cards: CF I,II / MD / MS / MS Pro / MS Duo / MS Pro Duo / SD / MMC / XD.
I located a very nice free image resizing program called VSO Image Resizer and promptly went about resizing all photos stored on the 1g card; some up to 5mb in size. I reduced the disk usage from 512mb to 30mb !
I wanted to copy some photos to the internal memory but they didn't have an appropriate cable (USB to mini-USB). I went shopping and a basic mini-usb to usb cable cost $27. Rediculous. Fortunately I passed by the console accessories aisle and found a mini-usb to usb and charger combo cable for the PSP for $4.95. I bought it and it worked fine.
Though with the Image Resizer program, the internal memory was sufficient to hold all their photos, it became clear that the easiest workflow would be for Sue to simply pull the 1gig card from the Picture Frame, plug it into her laptop which has a camera card slot, copy over the photos she wants and plug the card back into her Picture Frame.
I've been keeping my eyes open for a universal card adapter to buy. The Picture Frame with it's support for numerous cards could actually serve as an adapter to move files from one card to another. I was able to copy photos from Jane's new Sony Cybershot camera. She didn't have her USB pc cable but I was able to read her Memory Stick Pro Duo 2g card from the Picture Frame and connect my laptop using the cable I bought to download them.
Technology gets more accessible but remains as hard for normal folks to use.